I have used the product Zanfel once before for a bad case of poison oak. You can read my previous article. But what is in Zanfel that makes it work?
You can find the list of ingredients on the product packaging and also by searching the web. But, the specific active ingredient that does all the magic appears missing. The website notes that “U.S. and Foreign Patents Pending” so they probably don’t need to give away the secret just yet.
So, I decided to look into the known ingredients to see what I could find.

Listed below are the ingredients as found on the Zanfel packaging.
Looking at this list leads me to believe that Zanfel is simply a cleanser. Similar to Tecnu. Of specific interest are the ingredients Quaternium-15 and Triethanolamine. These are both known irritants and may cause allergic reactions! So, before using this product, be sure to follow any precautions and also to read through the ingredients. Note, the descriptions below are from my own quick sleuthing. They may or may not be correct. Let me know if you have corrections.
Cheers!
Zanfel Ingredients
- Polyethylene Granules - Used to help active ingredients penetrate better when applied.
- Sodium Lauroyl Sarcosinate - A weak anionic detergent (foaming/wetting agent).
- Nonoxynol-9 - Commonly used as a spermicide. But, also widely used as a biocide (disinfectant) in cosmetics, baby wipes, detergents and other products.
- C12-15 Pareth-9 - Typically used as sole detergent in highly alkaline laundry liquids and cleaning formulations.
- Disodium EDTA - (Disodium Ethylene–Diamine–Tetra–Acetate) Anionic Surfactant. A sodium salt of a mild organic acid and helps the system resist bacterial spoilage.
- Quaternium-15 - From http://www.dermnetnz.org/dna.acd/q-15.html Quaternium-15 is a formaldehyde-releasing preservative used in many cosmetics and pharmaceutical preparations. NOTE: Quaternium-15 may cause an allergic reaction with people that are either sensitive to formaldehyde or have a specific sensitivity. The reaction is normally a contact dermatitis.
- Carbomer 2% - Found in many hair and lotion products. Possibly a polymer and used as a thickening ingredient.
- Triethanolamine - From http://ntp-server.niehs.nih.gov/htdocs/IT-studies/imm90005.html Triethanolamine, produced along with mono- and diethanolamine by ammonolysis of ethylene oxide, is used in many cosmetics, fatty acid soaps, household detergents and emulsions, wood scouring, and as a water repellent in textiles. U. S. production and sales for 1989 was estimated to be 72 x 108 lb. Although triethanolamine is a skin, eye, and mucous membrane irritant, no information could be found on its sensitizing potential. From http://physchem.ox.ac.uk/MSDS/TR/triethanolamine.html May be harmful by inhalation, ingestion or through skin absorption. Chronic exposure may lead to liver and kidney damage. Skin irritant - may cause dermatitis. From http://umbbd.ahc.umn.edu/tea/tea_map.html Over 1.2 billion pounds of triethanolamine are produced annually in the United States. Triethanolamine is widely used as an ingredient in emulsifiers, thickeners, wetting agents, detergents, and alkalinizing agents in cosmetic products; as a chemical intermediate for anionic and nonionic surfactants and surface active agents in household cleaning agents, textiles, herbicides, pharmaceutical ointments, and other products; as a vulcanization accelerator in the manufacture of rubber; and in many other industrial applications.The National Cancer Institute nominated triethanolamine for study because of its widespread use in cosmetics and other consumer products, its high potential for worker exposure due to its many industrial uses, and its potential for conversion to the carcinogen N-nitrosodiethanolamine.
- Water - Our friend H2O!
That’s all folks! :)
Marisha
boarhog9
Doug
Paul
Hans
Paul Goldring
Hans
Bill
Bill
Bill
Lee
Hans
mkr
Lee
Hans
Hans
Hans
Serge
Cherie Johnson
Hans
Cherie - I’m not familiar with the product you describe but it sounds like a homeopathic remedy. I would be careful with those ‘remedies’. Here’s a good site with more information on poison oak and also homeopathic remedies: http://waynesword.palomar.edu/ww0802.htm
dave, OR
Anne
Deric Horn
Lucky (Al)
Lucky (Al)
Lucky (Al)
OK, I tried the Apricot Scrub a few hours ago. Here is mt opinion of the comparison:
Philip Batchelder
This ‘conversation’ is much appreciated, as is any product that helps in the short term without longterm nasty side effects! People should know that Prednisone can be very dangerous. What about Zanfel? I’ve found nothing conclusive, but a look at the product ingredient descriptions at the Environmental Working Group’s “Skin Deep” website indicates reasons for concern and cites scientific studies to back them up. (The site is quite a resource for checking out any of your bodycare products) Here are a few tidbits to add to the fine ingredient descriptions at the top of this thread:
Hans
Tom
Doug Spring
Hans
Steven
Ron
Crista
David S
Archie
Kyle Guthrie
LP
So that’s what happened to ImmuneOak. I took it for several years and it really worked for me. As I remember, I took three vials every summer. Each year my poison oak outbreaks were less and less until I only felt a little itchy for a day. My husband’s grandfather was PG&E and he gave it to me.
Bummer that they don’t make it any more.
Simon Waddington
Mike
Mike
Hans
Steven Traylor
steve
mark
loic
If you are very sensitive like me, there is only one recipe to follow each time yu go to a place where there might be some poison oak:
Steve
Mitzi Bergrud
Lee Dekker
Gunther
I sure would like to see some authoritative clinical studies, but then who would be stupid enough to voluntarily break out in PI for the trials?!? As it is, this anecdotal information is much like the old Elephant Repellent joke: I’ve applied it twice and haven’t seen a single elephant, thus I conclude it’s quite effective at repelling them. I’m currently on day 10 since exposure to p. oak, only 8 since the start of symptoms. I broke down and got a tube of Zanfel last night. A couple of comments:
Paul Spiegel
Nancy Sterner
Yoed Cameron
Cliff
I have read your Site with much gratitiude for the extensive focus on pi\po I found unfourtunatly that zanfel isn’t available directly in canada though I have ordered it, it will take “14 to 30 days” long past the time when this batch of pi will be gone .In frustration I applied a generic shampoo and a generic hand cleaner that had some of the same ingredients as Z I got some immediet relief and good long term relief with this simple test ,I’m going to forge ahead and try and synthezise a Zanfel clone and call it Zinfindel from the base of Zan-infedel" with strong recommondations that one does’nt try to drink it. Poison Ivy forces the mind into some dangerous places doesn’t it? I think I’ll use that as my defence of a civil suit ever comes forward. As I would recommend to our clypto-zanfel artist Mark who was obviously temporarily out of his mind when he risked a a shop lifting charge for a little tube of hope for relief .Anyway from the Patent office here is the listed formulation in the application.I should have paid more attention in chemistry but Dr Sholls and spermicide in a mean green base here I come
“Thus, a representative composition for the inventive solution might be polyethylene granules, sodium lauroyl sarcosinate, nonoxynol-9, C12-15 pareth-9, disodium EDTA, quaternium-15, carbomer 2%, triethanolamine, and water. " Cheers Cliff
christine k.
Debbie W.
Steve
Annie
Hans
Annie
Barry R. Nicholson
dave
Steven Traylor
adam
David Gurney
Lori
jan
Sam
Robin
Hans
Rick Kristian
scott
Tracy
Robert
Jane
Tom F
cindy
Hans
Tom - Good information. But I would like to note that I would not recommend taking prednisone as a deterent without a doctor’s recommendation. It can have bad side effects on your system. If you haven’t already, please talk to a doctor about the possible effects of taking it.
Cindy - There really isn’t any way to become less allergic to the poison. Once your body has learned the “signature” of the poison it reacts more and more. You can help to reduce the risk by applying barriers, washing after contact, etc.. There are a few “blocking” lotions on the market that you apply before venturing out.
Tom F
Hans
Jessica
RonH
Steve Moore
Hans
Jessica - Sounds like your son might have poison oak or ivy. Normally, at that stage you need to use a product like Zanfel. The oils that contain the poison have probably already been washed off so you need a treatment rather than a cleaner. Also, I don’t know if there are any issues with treating children. I would recommend talking with a dermatologist.
Steve - Interesting about drinking goat’s milk from a goat that consumes PO. But you also describe taking Immunoak at the same time. So it’s not possible to know if it was one or the other that helped you. Now, your comment about eating small bits of PO makes alarms start ringing. I would not recommend eating small bits of PO! The body treats PO as a toxin. As you have mentioned, you have become hypersensitive to PO. That’s because the body learns to recognize and attack the poisons from PO. Eating it may cause a very dangerous reaction. Another commenter on my site mentioned trying this experiment and learning the hard way it does not work. You can not become resistant to PO. Do not even try. I don’t know if dermatologists have PO allergy shots. They will treat severe cases of PO with prednisone. But note that prednisone can have side effects. So it’s not something to take without a doctor’s supervision.
Michelle
anne
anne
Dave
Hans
Ed Ryley
Karen
Todd
Todd
Kim Noller
Lyhue
ctrr03
For The People
GRF
GRF
Greta Sholachman
Hans
Greta Sholachman
Cheryl Watkins
twb
Mike
Brian Grove
Michael B
adam
Emilie
Brian
susan
Robin Chadwick
Erika
Erika
Chris from Houston
Brian
Kurt Funke
Kurt Funke
Danica
Heather
Patrick
Stan
.r a
C.J.
I was just wondering if you can pop the little bubbles, wash your hands, and apply your medicine.
am
am
am
Chris Thomas
I reached this website through Google. There are a number of products advertised on the sidebar. Do you have a comment on the effectiveness of All Stop?
AnneS
My husband is suffering from a bad case of poison ivy. He was pulling weeds in our backyard ( which is loaded with p.i.). on Sunday. He broke out on Monday. He’s in Canada working this week and I told him to buy Zanfel or tecnu and some benadryl. Tomorrow will be my turn. I was cutting back some overgrowth near my shed because I will be painting it soon, and I stepped in poison ivy and I know I touched it with my hands. I went to the local rite-aid and brought the zanfel, the rite-aid brand of zanfel, and some tecnu to the pharmacist and asked his opinion. He told me definitely not zanfel. He said that they got a paper telling them not to recommmend zanfel because studies have shown that it doesn’t work and it’s a huge waste of money for $39.99 a tube. He recommended benadryl and calagel. I opted for the tecnu extreme and a box of calagel with a trial size tecnu in it. I spent $21 instead of $40. I took the advice of some of you and showered immediately and used the St. Ives apricot scrub. I’ll put on the tecnu tonight and hopefully, I will have a mild to non existant case of poison ivy. Hubby bought some stuff in Canada. Some soap, benadryl and some cream, but he didn’t say what. He said he’s getting some relief, but man, he says he is covered head to toe and his private area. Poor guy!! What do you all think about the pharmacist not recommending zanfel?
carl
Bill
lou
Ben
Barbara
Diane Blankenship
m.vitkay
Terry
Anonymous
Jeanne Barnett
Charles
ted
Julianna
Julianna
Rose
Robert Wessel
jenjen
Jeff
Betsy
Jason Z
Eleanor
Eleanor
ronniereyes
Michelle
ronniereyes
Michelle
Update on my 11 year old son, after repeating the Walgreens brand of Zanfel the 2nd night, the itching came back the next night so I got some Technu Extreme. He said it still felt pretty good being rubbed in, but not as gritty as the Zanfel. I also applied vitamin E to all the areas since his skin looked so dry. The next morning it looked great (the itching was gone) but when he got home from school that afternoon, there was much more spreading & the new areas itched like crazy. So I just took him to the Dr. (since he’d already had it for 2 weeks…time to stop the madness!) & was prescribed some Prednizone tablets. After taking these for 24 hours, the PO was virtually gone! Anyway, I think the Zanfel & Technu Extreme scrubs work temporarily to stop the itching, but don’t help much with spreading. Plus I think my son is really allergic.
Lee Lee
JW
DG
Paul
Dan
Ellen
Jamie
francine
Chris
John
Jack
Rachel
Mugtoe
info
matt
JB
Cindy
Cindy
One more thing: Forgot to mention I did wash the dog of course, but I can’t keep washing him more than every two weeks or so because it’s not good for his skin to get dried out with repeated baths.
AlsoNate
Laurence D Cohen
Scott
paxpeg
vauron
Doug
tz
lala
Mike
Wayne Touchstone
artie
Pat
Don’t you people realize the Poison Oak/Ivy is on your keyboards! The more you type here, the more it spreads!!! Kidding. Maybe. Great site. Here’s what works for me:
john
This is my second entry.
Excluding my first entry, I’ve seen at least 7+ other PI itch remedies which use hot water. Do you think that this is a coincidence? It really works for me and also a few other people that I’ve shown the method to.
First one must obviously thoroughly wash off all PI oils with liberal amounts of soap and cold water. Probably some time after you might even consider taking a shower & a change of clothes (slight humor).
The hot water itch reduction method does not cure PI and I only use it for ITCH RELIEF after I’ve washed up. This is not a miracle cure, but it will more than likely produce several hours (helping you to get to sleep) to slightly more than a day of itch free time (providing you are not sweating) to allow one to experience other more pleasurable thoughts and activies in place of constant scratching & popping blisters.
It is important to mention that this method can NOT be used ANYWHERE on the face or on difficult to reach areas on the body. And this method should NOT be used for severe exposure. I done correctly it should eliminate the need to scratch for a significant duration.
The method (similar to other entries above)is to place PI afflicted body part/area under warm water and gradually increase water temperature until you almost can’t stand it; count to approximately 5 to 10 seconds, withdraw immediately and DRY thoroughly. (Refer to entries 48, 60, 119 and 130) Blow dryer hot air treatment can be used for hard to reach areas (excluding the face)but is not nearly as effective; I only use this if I am extremely desperate to stop the itching.
When I get exposure all over hands & arms, one of my worst areas are between the fingers where the irritation can go beyond itching to sometimes a burning sensation (through to the bone); I have found the hot water method to be very effective there.
It is crucial that you thoroughly wash to remove all external PI oils (as soon as possible after exposure)with what ever treatment you use.
Hot water method can also be effective in temporarily eliminating itching from mosquito bites and for yellow jacket stings after a day or two when the sting subsides and the itching starts.
As far as the rationale that medicines and pharmaceuticals are not priced according to their ingredients, who cares. There is no way I will pay even $5 (let alone $40) for topical creams (some people say work and others say don’t) that I need to apply regularly when I can apply hot water at no cost; it still works for me. If the creams worked so well people would not be experimenting with or looking for other remedies. Maybe it is that everyone’s body reacts and responds differently.
hans
Gary & Donna Davis
Dennis
Alternative method of stopping Poison Ivy itching for good.******
Today, January 10, starting with January the 8th I have been in agony and back. The itching was unbearable. I ended up rubbing my eyes and the eye lids were on fire. Nothing I tried worked. Alcohol used to do it years ago, but this time it only cooled things off for a while. The DomeBoro aluminum acetate they promised me at the drug store had no effect. The soaps work for 15 minutes and you have to take a shower again if you want the itching to stop. I tried many things and I don’t want to use drugs. I was looking of a natural source of help. I believe I found it and I am happy to share it with you. There is no charge or gimmick leading to a sale. But if you the whole post you will know why this works and perhaps you can make more contributions to solve this problem once and for all without bleeding people with $40 per ounce creams which do not works half of the time.
So, let me continue. In desperation I tried something different. I read many of the postings above, in order to understand how to approach the problem. And the itching was killing me all along. In another article I read something about how urushiol acts on the skin and exposes it to opportunistic bacteria and the lights went on. The itching is mostly the invasive bacteria not the oil. If you don’t believe me, wash an infected spot on your body with the soap until the itching stops and protect it from the outside with a large bandage. It will take longer for the itching to return.
With that in the pocket I wondered what could suppress the opportunistic bacteria and remove the urushiol resin. Water and soap sounds good, but this resin does not emulsify that well with soap, hence the rash continues and the skin is still exposed. So, the bacteria returns from air particles or contact with objects and peole etc… and a new colony starts to multiply. Apparently, urushiol is a resin. Resins require various density oils to be dissolved, so soaps are not that effective to begin with. Alcohol as an oil is effective early in the game but by the time you notice the itching it is too late. And we are dealing with just such a case here.
The question is this. Can you think of a safe ingredient which will suppress bacteria permanently on the skin? Water and alcohol will evaporate and you are back to square one. Creams and oils can cause further irritation and who knows what ingredients are in some creams. But creams are the right idea if you want to protect the skin from new infections. But which cream can act as a barrier as well as an antibacterial for the skin as well as calming, not irritating the skin further?
Now if that substance could further dissolve or dilute urushiol, WOW! We are talking about killing two birds with a stone. And there is such a substance. It is coconut oil. But that is not all you need to know. You need to make sure that it is not rancid, however. Rancid oils are irritants and can be carcinogenic. Many oils sold in health food stores are rancid because they have been heated in processing. I leave that to you to research. Rancid oils have a peculiar odor, so learn to detect it by smell on your own.
So, coconut oil definitely soothes the itch except for the very damaged part where blisters are forming and the wound is oozing. In those areas the resin has moved down the strata of the skin and opportunistic bacteria have moved down with it, so covering the top layer of the skin with coconut oil does not stop the itching there.
What I did was to rub those areas with the coconut oil vigorously, not with my nails, the with the soft part of the fingertips until the itching stops. The nice thing about that is that two actions take place. Coconut oil is thin enough to move into the strata of the skin and kill the bacteria deep under, as well as displace urushiol by dissolution. Every time you rub the coconut molecules dissolve the resin separating its molecules further and further apart, spreading and forcing a good amount of urushiol to the surface.
Because of that, you must also use something clean, like a paper towel or anything you know is sterilized, to remove the urushiol and the dead bacteria that is displaced to the surface. Coconut oil kills bacteria to begin with. And it is very friendly to human skin. It is as safe as could be, except for some weird folk, perhaps. It is also the best oil you can use in cooking, bar none. And if you do not have oozing sores from poison ivy/oak/sumac it will stop the itching on contact. The rubbing moves the oil down into the skin and the infection dies rapidly.
In sum, for those who did not want to read everything.
-Use healthy coconut oil (I use Carrington Farms from Costco but there are others) -Rub it in vigorously and as you rub it the itching will subside with every rub.
-When the itching stops use a clean paper towel/sterilized cloth to remove the oil -Then cover the area in oil and let the skin absorb it. -When the skin absorbs it, add more oil with a little rub and keep it up
But on oozing areas keep the rubbing for longer. After a while it will suddenly stop. That means that the coconut oil arrived at its destination and the bacteria stopped chewing. It takes time to do that, but well worth the effort.
And please do not use your fingernails to scratch, else you will make things worse. Fingernails have horrid and vile bacteria which can make things far worse for you. Cut your fingernails off and brush them thoroughly with antibacterial soap. We are talking surgery type of clean hands, here. You don’t want to introduce new colonies of bacteria into an open wound.
Good luck. My itching is way way better. And any spot that restarts I treat early. I have successfully stopped the infection on my eyelids too. In fact that was the first thing I treated wit the coconut oil.
I wish you well and spread this idea to others. The solution is very simple.
Dennis
Let me add this for those who have not started any treatment yet. Before starting with the coconut oil, as I have written about above, if you have not taken a shower and washed your clothes and everything you touched on the way in, you need to do that first. Doorknobs, drawer handles dishes what ever you touched should be washed. The coconut application and the rubbing can spread all the urushiol resin on other parts of your body and you will be on agony street like me.
Take a shower and use alcohol with sterile pads to clean all the sores thoroughly, first! Then apply the coconut oil and rub it in to stop the infection and further reduce the urushiol density within the skin.
Keep washing and washing things manically.
Regards,
Dennis
Dave
Great point. I’ve used Tecnu and Dawn dishwashing at “Stage 1”, initial cleanse.
In fact, at 1st notice of P.I., I cleanse the heck out of the localized spot… REALLY WELL! Then I move on to my whole body, hair and all in a tolerably cool shower (warm enough not to be in shock) and rinse. I do that twice. Finally, before bedtime, I do another “Stage 1” cleanse again.
I’m sure the process sounds a little nutty, and maybe OCD to some degree. But I am WICKED allergic to all things Urushiol. That said, I’m suffering from one of my worst break-outs as I type this. Why?
Well, I didn’t know I had it. It was days before I realized it was actually P.I. and not itching from a swarm of no-see-ums. I’m new to Montana from Hawaii and I didn’t get any P.I. during my decade in HI, so I kind of got lackadaisical about the P.I. process that I developed while in California with Poison Oak.
But I was working on my boat dock here in Montana in the evening as the daylight was fading, I assumed the itch was from the swarm of bugs I was batting away as I finished up my task (this is my second summer here, so I’m still a bit of a greenhorn).
With that in mind, I was amazed at how crazy-itchy it was, and now that I look back, I was pretty stupid not to recognize the telltale symptoms. It wasn’t until a rash of blistered appeared and I knew I was too late. But still, I
I haven’t tried the “Stage 2” coconut oil yet, but plan to next time - or maybe later with this bout if my current situation doesn’t respond to the medication. Yup, I went to the clinic today and they immediately got me on Prednisone. It works for me, actually twice before in my life. And when things get to the oozing-rash stage, there’s no other way for me to go. Because it seems like my immune response is in overdrive and it won’t quit “responding” to the Urushiol invasion.
And that’s why I’m going to try the Coconut Oil Stage 2 of my new process. Hopefully it will mitigate what’s already been soaked-in before cleansing, or what’s been left behind.
Thanks for your insights!
Dennis
The gentleman who posted about the hot water is correct. What the hot water does is kill the bacteria which cases the itching. That supports the idea that the itching is bacteria based. But reducing the urushiol resin in your skin is achieved better with coconut oil with the process of reduction. The rubbing disperses the resin and the coconut oil allows it to slide back up where you can remove it with a sterile paper or cotton product. Coconut further shields the skin from subsequent infections. Bacteria cannot live in coconut oil.
Regards,
nielsen
magic ingredient = nonoxynol 9. endocrine disruptor. sometime medicine, sometime poison.
http://en.wikipedia.org/wiki/Nonylphenol
diane spence
Walter Bliss